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Cannabis dependence symptom count

CSMD1 · rs77378271

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cannabis dependence symptom count compared to the general population. (GWAS Catalog, JAMA Psychiatry 2016, PMID:27028160)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cannabis dependence symptom count. (GWAS Catalog, JAMA Psychiatry 2016, PMID:27028160)

G/G Published research associates this genotype with typical/baseline likelihood of Cannabis dependence symptom count — no copies of the reported risk allele. (GWAS Catalog, JAMA Psychiatry 2016, PMID:27028160)

Source: GWAS Catalog, JAMA Psychiatry 2016, PMID:27028160

Questions about rs77378271

What is rs77378271?

rs77378271 is a single position in the genome, in or near the CSMD1 gene. Published research associates it with cannabis dependence symptom count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs77378271 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77378271 come from?

GWAS Catalog, JAMA Psychiatry 2016, PMID:27028160. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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