Parkinson's disease or first degree relation to individual with Parkinson's disease
CRLS1 · rs77351827
0 21712317Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 15,056 European ancestry cases, 18,618 European ancestry proxy cases, 449,056 European ancestry controls; replicated in 22,632 European ancestry cases, 968,735 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0802 higher (95% confidence interval 0.053-0.107); p = 9 × 10−9.
How common The T allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 20, band 20p12.3 — in an intron of CRLS1.
What each result means
C/CNo copy of the version the research linked to Parkinson's disease or first degree relation to individual with Parkinson's disease. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Parkinson's disease or first degree relation to individual with Parkinson's disease. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Parkinson's disease or first degree relation to individual with Parkinson's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs77351827 is a single position in the genome, in or near the CRLS1 gene. Published research associates it with parkinson's disease or first degree relation to individual with parkinson's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs77351827 linked to?
On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs77351827 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs77351827 come from?
GWAS Catalog, Lancet Neurol 2019, PMID:31701892. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 21712317Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI7Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Parkinson's disease or first degree relation to individual with Parkinson's disease (rs77351827). MyGeneLog™. https://www.mygenelog.com/variants/rs77351827