CYP19A1 · rs77348531
Where this position leads
Condition: Pulmonary Function (Lung Capacity)
What the study found
Who was studied 129,680 East Asian ancestry individuals.
The effect Each copy of the G allele shifted the measure 0.0204 higher (95% confidence interval 0.013-0.028); p = 4 × 10−8.
Where it sits Chromosome 15, band 15q21.2 — in an intron of CYP19A1.
rs77348531 is a single position in the genome, in or near the CYP19A1 gene. Published research associates it with forced expiratory volume in 1 second (fev1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Pulmonary Function (Lung Capacity). The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature genetics 2026, PMID:41565855. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Forced expiratory volume in 1 second (FEV1) (rs77348531). MyGeneLog™. https://www.mygenelog.com/variants/rs77348531