Who was studied 14,992 East Asian ancestry cases, 146,214 East Asian ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.365 lower (95% confidence interval 0.28-0.45); p = 5 × 10−17.
How common The A allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 13, band 13q12.3 — in an intron of FLT1.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Myocardial infarction compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Myocardial infarction.
G/GPublished research associates this genotype with typical/baseline likelihood of Myocardial infarction — no copies of the reported risk allele.
rs77330370 is a single position in the genome, in or near the FLT1 gene. Published research associates it with myocardial infarction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs77330370 linked to?
On MyGeneLog this position is linked to Myocardial Infarction. The research behind each link, and its sources, are set out on that condition page.
Does having rs77330370 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs77330370 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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