Standard

Urinary albumin excretion

CWC27 · rs7731168

Where this position leads

Condition: Kidney Function

rs7731168 Condition: Kidney Function Kidney Function Condition rs7731168 rs7731168 CWC27

What the study found

Who was studied 382,500 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0125 higher (95% confidence interval 0.0087-0.0164); p = 2 × 10−10.

How common The C allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 5, band 5q12.3 — in an intron of CWC27.

What each result means

C/C Two copies of the version the research linked to Urinary albumin excretion. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Urinary albumin excretion. That is a smaller link than two copies.
G/G No copy of the version the research linked to Urinary albumin excretion. This is the starting point the study compared everyone against.
Source

Questions about rs7731168

What is rs7731168?

rs7731168 is a single position in the genome, in or near the CWC27 gene. Published research associates it with urinary albumin excretion. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7731168 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs7731168 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7731168 come from?

GWAS Catalog, Am J Hum Genet 2018, PMID:30220432. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Urinary albumin excretion (rs7731168). MyGeneLog™. https://www.mygenelog.com/variants/rs7731168

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