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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 48,433 East Asian ancestry individuals; replicated in 4,992 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.097 higher (95% confidence interval 0.072-0.122); p = 1 × 10−13.
How common The A allele had a frequency of about 7% in the people studied.
Where it sits Chromosome 6, band 6q24.3 — in an intron of RAB32.
What each result means
A/ATwo copies of the version the research linked to Skin luminance. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Skin luminance. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Skin luminance. This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 38849341 · open access
Questions about rs77310623
What is rs77310623?
rs77310623 is a single position in the genome, in or near the RAB32 gene. Published research associates it with skin luminance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs77310623 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs77310623 come from?
GWAS Catalog, Nature communications 2024, PMID:38849341. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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