Standard

Insomnia

TRPC7 · rs7727558

Where this position leads

Condition: Insomnia

rs7727558 Condition: Insomnia Insomnia Condition rs7727558 rs7727558 TRPC7

What the study found

Who was studied 593,724 European ancestry cases, 1,771,286 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.009 lower (95% confidence interval 0.007-0.011); p = 1 × 10−15.

Where it sits Chromosome 5, band 5q31.1 — in an intron of TRPC7.

What each result means

G/G No copy of the version the research linked to Insomnia. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Insomnia. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Insomnia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7727558

What is rs7727558?

rs7727558 is a single position in the genome, in or near the TRPC7 gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7727558 linked to?

On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.

Does having rs7727558 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7727558 come from?

GWAS Catalog, Nature genetics 2022, PMID:35835914. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs7727558). MyGeneLog™. https://www.mygenelog.com/variants/rs7727558

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