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Who was studied 56 Greater Middle Eastern ancestry cases, 5 unknown ancestry cases, 36 Greater Middle Eastern ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 9 × 10−11.
How common The A allele had a frequency of about 32% in the people studied.
Where it sits Chromosome 19, band 19p13.12 — a missense change in BRME1.
What each result means
A/ATwo copies of the version the research linked to Hodgkin's lymphoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Hodgkin's lymphoma. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Hodgkin's lymphoma. This is the starting point the study compared everyone against.
International journal of laboratory hematology · 2021 · PMID 34216518
Questions about rs77270337
What is rs77270337?
rs77270337 is a single position in the genome, in or near the C19orf57 gene. Published research associates it with hodgkin's lymphoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs77270337 linked to?
On MyGeneLog this position is linked to Hodgkin Lymphoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs77270337 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs77270337 come from?
GWAS Catalog, International journal of laboratory hematology 2021, PMID:34216518. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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