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Ceramide (d19:1/24:0) levels

LINC01723 · rs77229235

What the study found

Who was studied 4,492 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.467 higher (95% confidence interval 0.37-0.56); p = 6 × 10−22.

Where it sits Chromosome 20, band 20p12.1 — in an intron of LINC01723.

What each result means

A/A No copy of the version the research linked to Ceramide (d19:1/24:0) levels. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Ceramide (d19:1/24:0) levels. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Ceramide (d19:1/24:0) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs77229235

What is rs77229235?

rs77229235 is a single position in the genome, in or near the LINC01723 gene. Published research associates it with ceramide (d19:1/24:0) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs77229235 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77229235 come from?

GWAS Catalog, Nature communications 2022, PMID:35668104. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Ceramide (d19:1/24:0) levels (rs77229235). MyGeneLog™. https://www.mygenelog.com/variants/rs77229235

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