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Histidine-rich glycoprotein levels

HRG-AS1 · rs77190643

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.632 higher (95% confidence interval 0.53-0.74); p = 3 × 10−32.

How common The T allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 3, band 3q27.3 — in an intron of HRG-AS1.

What each result means

C/C No copy of the version the research linked to Histidine-rich glycoprotein levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Histidine-rich glycoprotein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Histidine-rich glycoprotein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs77190643

What is rs77190643?

rs77190643 is a single position in the genome, in or near the HRG-AS1 gene. Published research associates it with histidine-rich glycoprotein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs77190643 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77190643 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Histidine-rich glycoprotein levels (rs77190643). MyGeneLog™. https://www.mygenelog.com/variants/rs77190643

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