Standard
Lung function (FEV1)
HTR4 · rs7715901
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Lung function (FEV1) — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lung function (FEV1).
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lung function (FEV1) compared to the general population.
Source
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
Wain LV,
Shrine N,
Artigas MS,
Erzurumluoglu AM,
Noyvert B,
Bossini-Castillo L,
Obeidat M,
Henry AP,
Portelli MA,
Hall RJ,
Billington CK,
Rimington TL
and 94 more — show all
Fenech AG,
John C,
Blake T,
Jackson VE,
Allen RJ,
Prins BP,
Campbell A,
Porteous DJ,
Jarvelin MR,
Wielscher M,
James AL,
Hui J,
Wareham NJ,
Zhao JH,
Wilson JF,
Joshi PK,
Stubbe B,
Rawal R,
Schulz H,
Imboden M,
Probst-Hensch NM,
Karrasch S,
Gieger C,
Deary IJ,
Harris SE,
Marten J,
Rudan I,
Enroth S,
Gyllensten U,
Kerr SM,
Polasek O,
Kähönen M,
Surakka I,
Vitart V,
Hayward C,
Lehtimäki T,
Raitakari OT,
Evans DM,
Henderson AJ,
Pennell CE,
Wang CA,
Sly PD,
Wan ES,
Busch R,
Hobbs BD,
Litonjua AA,
Sparrow DW,
Gulsvik A,
Bakke PS,
Crapo JD,
Beaty TH,
Hansel NN,
Mathias RA,
Ruczinski I,
Barnes KC,
Bossé Y,
Joubert P,
van den Berge M,
Brandsma CA,
Paré PD,
Sin DD,
Nickle DC,
Hao K,
Gottesman O,
Dewey FE,
Bruse SE,
Carey DJ,
Kirchner HL,
Jonsson S,
Thorleifsson G,
Jonsdottir I,
Gislason T,
Stefansson K,
Schurmann C,
Nadkarni G,
Bottinger EP,
Loos RJ,
Walters RG,
Chen Z,
Millwood IY,
Vaucher J,
Kurmi OP,
Li L,
Hansell AL,
Brightling C,
Zeggini E,
Cho MH,
Silverman EK,
Sayers I,
Trynka G,
Morris AP,
Strachan DP,
Hall IP,
Tobin MD
Nature genetics · 2017 · PMID 28166213 · open access
Questions about rs7715901
What is rs7715901?
rs7715901 is a single position in the genome, in or near the HTR4 gene. Published research associates it with lung function (fev1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7715901 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7715901 come from?
GWAS Catalog, Nat Genet 2017, PMID:28166213. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants