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Male-pattern baldness

near RORB · rs77123275

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs77123275 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs77123275 rs77123275 near RORB

What the study found

Who was studied 205,327 European ancestry males.

The effect Each copy of the T allele shifted the measure 0.0676 higher (95% confidence interval 0.054-0.082); p = 3 × 10−21.

How common The T allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 9, band 9q21.13 — in an intron of RORB-AS1.

What each result means

C/C No copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs77123275

What is rs77123275?

rs77123275 is a single position in the genome, in or near the near RORB gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs77123275 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs77123275 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77123275 come from?

GWAS Catalog, Nat Commun 2018, PMID:30573740. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Male-pattern baldness (rs77123275). MyGeneLog™. https://www.mygenelog.com/variants/rs77123275

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