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Cholesterol efflux capacity

LPL · rs77069344

What the study found

Who was studied 3,487 French-Canadian ancestry cases, 1,806 French-Canadian ancestry controls.

The effect Each copy of the G allele shifted the measure 0.201 higher (95% confidence interval 0.14-0.26); p = 8 × 10−10.

How common The G allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 8, band 8p21.3 — in an intron of LPL.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cholesterol efflux capacity compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cholesterol efflux capacity.
T/T Published research associates this genotype with typical/baseline likelihood of Cholesterol efflux capacity — no copies of the reported risk allele.
Source

Questions about rs77069344

What is rs77069344?

rs77069344 is a single position in the genome, in or near the LPL gene. Published research associates it with cholesterol efflux capacity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs77069344 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77069344 come from?

GWAS Catalog, J Am Heart Assoc 2018, PMID:30369316. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cholesterol efflux capacity (rs77069344). MyGeneLog™. https://www.mygenelog.com/variants/rs77069344

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