Sensitive

Hepatocellular carcinoma

near MAP3K9-DT · rs77052733

Where this position leads

Condition: HBV-Related Hepatocellular Carcinoma

rs77052733 Condition: HBV-Related Hepatocellular Carcinoma HBV-Related Hepatocellular Carcinoma Condition rs77052733 rs77052733 near MAP3K9-…

What the study found

Who was studied 977 African ancestry cases, 120,676 African ancestry controls, 630 Hispanic or Latin American cases, 59,146 Hispanic or Latin American controls, 7,355 East Asian ancestry cases, 629,454 East Asian ancestry controls, 8,216 European ancestry cases, 1,558,609 European ancestry controls, 519 cases, 347,798 controls.

The effect Each copy of the T allele shifted the measure 0.007 higher (95% confidence interval 0.0037-0.0103); p = 3 × 10−8.

How common The T allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 14, band 14q24.2 — between genes, 2.2 kb from MAP3K9-DT.

What each result means

C/C No copy of the version the research linked to Hepatocellular carcinoma. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Hepatocellular carcinoma. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Hepatocellular carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs77052733

What is rs77052733?

rs77052733 is a single position in the genome, in or near the near MAP3K9-DT gene. Published research associates it with hepatocellular carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs77052733 linked to?

On MyGeneLog this position is linked to HBV-Related Hepatocellular Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs77052733 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77052733 come from?

GWAS Catalog, HGG advances 2026, PMID:42357869. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hepatocellular carcinoma (rs77052733). MyGeneLog™. https://www.mygenelog.com/variants/rs77052733

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