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Platelet forward scatter distribution width

P4HA2 · rs7705189

What the study found

Who was studied 29,618 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0772 SD units lower (95% confidence interval 0.061-0.093); p = 1 × 10−21.

How common The G allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 5, band 5q31.1 — inside P4HA2.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Platelet forward scatter distribution width — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Platelet forward scatter distribution width.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Platelet forward scatter distribution width compared to the general population.
Source

Questions about rs7705189

What is rs7705189?

rs7705189 is a single position in the genome, in or near the P4HA2 gene. Published research associates it with platelet forward scatter distribution width. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7705189 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7705189 come from?

GWAS Catalog, Nature communications 2023, PMID:37596262. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Platelet forward scatter distribution width (rs7705189). MyGeneLog™. https://www.mygenelog.com/variants/rs7705189

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