Standard

Uterine fibroids

DLEU7 · rs770397

Where this position leads

Condition: Uterine Fibroids

rs770397 Condition: Uterine Fibroids Uterine Fibroids Condition rs770397 rs770397 DLEU7

What the study found

Who was studied 53,711 European ancestry female cases, 380,441 European ancestry female controls, 14,905 East Asian ancestry female cases, 69,609 East Asian ancestry female controls, 14,905 Central Asian ancestry female cases, 69,609 Central Asian ancestry female controls, 14,905 South Asian ancestry female cases, 69,609 South Asian ancestry female controls, 5,678 African ancestry female cases, 15,760 African ancestry female controls.

The effect Each copy of the T allele shifted the measure 0.0803 lower (95% confidence interval 0.058-0.102); p = 8 × 10−13.

Where it sits Chromosome 13, band 13q14.3 — inside DLEU7.

What each result means

G/G No copy of the version the research linked to Uterine fibroids. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Uterine fibroids. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Uterine fibroids. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs770397

What is rs770397?

rs770397 is a single position in the genome, in or near the DLEU7 gene. Published research associates it with uterine fibroids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs770397 linked to?

On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.

Does having rs770397 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs770397 come from?

GWAS Catalog, Nature communications 2025, PMID:40050615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Uterine fibroids (rs770397). MyGeneLog™. https://www.mygenelog.com/variants/rs770397

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