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Antisaccade task score

OR13C9 · rs77038697

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls.

The effect Each copy of the A allele shifted the measure 0.235 lower (95% confidence interval 0.16-0.31); p = 3 × 10⁻⁸.

Where it sits Chromosome 9, band 9q31.1 — in an intron of LOC107987105.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Antisaccade task score compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Antisaccade task score.

G/G Published research associates this genotype with typical/baseline likelihood of Antisaccade task score — no copies of the reported risk allele.

Source

Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study

Greenwood TA, Lazzeroni LC, Maihofer AX, Swerdlow NR, Calkins ME, Freedman R, Green MF, Light GA, Nievergelt CM, Nuechterlein KH, Radant AD, Siever LJ

and 9 more — show all

Silverman JM, Stone WS, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Gur RC, Gur RE, Braff DL

JAMA psychiatry · 2019 · PMID 31596458

Questions about rs77038697

What is rs77038697?

rs77038697 is a single position in the genome, in or near the OR13C9 gene. Published research associates it with antisaccade task score. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs77038697 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77038697 come from?

GWAS Catalog, JAMA Psychiatry 2019, PMID:31596458. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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