Standard

Urea levels

near FGFR4 · rs7703225

Where this position leads

Condition: Gout

rs7703225 Condition: Gout Gout Condition rs7703225 rs7703225 near FGFR4

What the study found

Who was studied 342,286 European ancestry individuals, 6,015 African ancestry individuals, 7,336 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0224 higher (95% confidence interval 0.016-0.029); p = 1 × 10−10.

Where it sits Chromosome 5, band 5q35.3 — between genes, 5.5 kb from FGFR4.

What each result means

A/A Two copies of the version the research linked to Urea levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Urea levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Urea levels. This is the starting point the study compared everyone against.
Source

Questions about rs7703225

What is rs7703225?

rs7703225 is a single position in the genome, in or near the near FGFR4 gene. Published research associates it with urea levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7703225 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs7703225 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7703225 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Urea levels (rs7703225). MyGeneLog™. https://www.mygenelog.com/variants/rs7703225

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