Standard

Triglycerides

ACOXL · rs77004761

Where this position leads

Condition: High Triglycerides

rs77004761 Condition: High Triglycerides High Triglycerides Condition rs77004761 rs77004761 ACOXL

What the study found

Who was studied 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.039 higher; p = 7 × 10−10.

Where it sits Chromosome 2, band 2q13 — in an intron of MIR4435-2HG.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Triglycerides — no copies of the reported risk allele.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Triglycerides.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Triglycerides compared to the general population.
Source

Questions about rs77004761

What is rs77004761?

rs77004761 is a single position in the genome, in or near the ACOXL gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs77004761 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

Does having rs77004761 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77004761 come from?

GWAS Catalog, Nat Genet 2018, PMID:29507422. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides (rs77004761). MyGeneLog™. https://www.mygenelog.com/variants/rs77004761

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