Standard

Cystatin C levels

FNDC3A · rs77003779

Where this position leads

Condition: Gout

rs77003779 Condition: Gout Gout Condition rs77003779 rs77003779 FNDC3A

What the study found

Who was studied 342,399 European ancestry individuals, 6,015 African ancestry individuals, 7,338 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0625 lower (95% confidence interval 0.053-0.072); p = 9 × 10−35.

Where it sits Chromosome 13, band 13q14.2 — in an intron of FNDC3A.

What each result means

A/A No copy of the version the research linked to Cystatin C levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Cystatin C levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Cystatin C levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs77003779

What is rs77003779?

rs77003779 is a single position in the genome, in or near the FNDC3A gene. Published research associates it with cystatin c levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs77003779 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs77003779 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77003779 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cystatin C levels (rs77003779). MyGeneLog™. https://www.mygenelog.com/variants/rs77003779

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