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Sex hormone-binding globulin levels adjusted for BMI

near UGT2B15 · rs7696472

What the study found

Who was studied 368,929 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.013 higher (95% confidence interval 0.011-0.015); p = 8 × 10−58.

How common The A allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 4, band 4q13.2 — between genes, 1.8 kb from UGT2B15.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Sex hormone-binding globulin levels adjusted for BMI compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Sex hormone-binding globulin levels adjusted for BMI.
G/G Published research associates this genotype with typical/baseline likelihood of Sex hormone-binding globulin levels adjusted for BMI — no copies of the reported risk allele.
Source

Questions about rs7696472

What is rs7696472?

rs7696472 is a single position in the genome, in or near the near UGT2B15 gene. Published research associates it with sex hormone-binding globulin levels adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7696472 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7696472 come from?

GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sex hormone-binding globulin levels adjusted for BMI (rs7696472). MyGeneLog™. https://www.mygenelog.com/variants/rs7696472

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