A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Alzheimer disease and age of onset compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Alzheimer disease and age of onset.
G/GPublished research associates this genotype with typical/baseline likelihood of Alzheimer disease and age of onset — no copies of the reported risk allele.
Molecular psychiatry · 2016 · PMID 26830138 · open access
Questions about rs76930906
What is rs76930906?
rs76930906 is a single position in the genome, in or near the near FBXO8 gene. Published research associates it with alzheimer disease and age of onset. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs76930906 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs76930906 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs76930906 come from?
GWAS Catalog, Mol Psychiatry 2016, PMID:26830138. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.