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Iris color (b* coordinate)

OCA2 · rs76930569

What the study found

Who was studied 377 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.527 higher (95% confidence interval 0.38-0.67); p = 5 × 10−12.

How common The T allele had a frequency of about 62% in the people studied.

Where it sits Chromosome 15, band 15q13.1 — in an intron of OCA2.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Iris color (b* coordinate) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Iris color (b* coordinate).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Iris color (b* coordinate) compared to the general population.
Source

Questions about rs76930569

What is rs76930569?

rs76930569 is a single position in the genome, in or near the OCA2 gene. Published research associates it with iris color (b* coordinate). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs76930569 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76930569 come from?

GWAS Catalog, PeerJ 2017, PMID:29109912. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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