4 4714325211226Reads by AI crawlersClaude1ChatGPT4Google · Gemini3Perplexity2Meta AI5Microsoft · Copilot2Amazon1Apple1China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others26Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
C/CTwo copies of the common allele. Published research does not associate this genotype with elevated odds of losing smell or taste during a COVID-19 infection.
C/TOne copy of the variant allele. Published research associates each copy with about 1.11 to 1.12 times higher odds of losing smell or taste during COVID-19, compared with people carrying none. UGT2A1 and UGT2A2 are expressed in the olfactory tissue that lines the nose and are involved in clearing odorant molecules after they are detected.
T/TTwo copies of the variant allele. Published research associates this genotype with the highest odds of COVID-19 related loss of smell or taste among the three, though the effect is modest — this shifts a probability, it does not determine the outcome.
This describes one symptom of one infection and says nothing about how severe a case of COVID-19 would be. Loss of smell that persists after an infection is worth raising with a doctor.
rs7688383 is a single position in the genome, in or near the UGT2A1 / UGT2A2 gene. Published research associates it with covid-19 related loss of smell or taste. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7688383 linked to?
On MyGeneLog this position is linked to Smell Perception and Specific Anosmias. The research behind each link, and its sources, are set out on that condition page.
Does rs7688383 affect smell or taste?
This position sits in the COVID-19 and Smell/Taste Loss group on the chemosensory axis. Chemosensory variants do not shift a risk — they change the perception itself, which makes them the rarest thing on this site: genetics you can check on yourself.
Does having rs7688383 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7688383 come from?
Shelton et al. 2022, Nature Genetics — the UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste (PMID 35039640); 33,336 cases and 16,257 controls of European ancestry with Latino replication, odds ratio 1.11-1.12 per T allele. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
4 4714325211226Reads by AI crawlersClaude1ChatGPT4Google · Gemini3Perplexity2Meta AI5Microsoft · Copilot2Amazon1Apple1China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others26Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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COVID-19 related loss of smell or taste (rs7688383). MyGeneLog™. https://www.mygenelog.com/variants/rs7688383