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Putamen iron levels (R2* MRI)

ACSL1 · rs7680850

What the study found

Who was studied 39,533 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.046 higher (95% confidence interval 0.032-0.06); p = 1 × 10−11.

Where it sits Chromosome 4, band 4q35.1 — in an intron of ACSL1.

What each result means

C/C No copy of the version the research linked to Putamen iron levels (R2* MRI). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Putamen iron levels (R2* MRI). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Putamen iron levels (R2* MRI). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7680850

What is rs7680850?

rs7680850 is a single position in the genome, in or near the ACSL1 gene. Published research associates it with putamen iron levels (r2* mri). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7680850 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7680850 come from?

GWAS Catalog, Neurobiology of disease 2024, PMID:38789058. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Putamen iron levels (R2* MRI) (rs7680850). MyGeneLog™. https://www.mygenelog.com/variants/rs7680850

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