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Who was studied 27 Taiwanese ancestry cases, 142 Taiwanese ancestry controls.
The effect
Each copy of the G allele carried 42.15 times the odds of Restless legs syndrome in migraine without aura; p = 2 × 10−8.
How common The G allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 12, band 12q23.2 — in a non-coding transcript of HELLPAR.
What each result means
G/GTwo copies of the version the research linked to Restless legs syndrome in migraine without aura. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Restless legs syndrome in migraine without aura. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Restless legs syndrome in migraine without aura. This is the starting point the study compared everyone against.
Annals of clinical and translational neurology · 2020 · PMID 32918390 · open access
Questions about rs76770509
What is rs76770509?
rs76770509 is a single position in the genome, in or near the near PMCH gene. Published research associates it with restless legs syndrome in migraine without aura. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs76770509 linked to?
On MyGeneLog this position is linked to Restless Legs Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does having rs76770509 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs76770509 come from?
GWAS Catalog, Ann Clin Transl Neurol 2020, PMID:32918390. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Restless legs syndrome in migraine without aura (rs76770509). MyGeneLog™. https://www.mygenelog.com/variants/rs76770509