G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Restless legs syndrome in migraine without aura compared to the general population. (GWAS Catalog, Ann Clin Transl Neurol 2020, PMID:32918390)
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Restless legs syndrome in migraine without aura. (GWAS Catalog, Ann Clin Transl Neurol 2020, PMID:32918390)
T/TPublished research associates this genotype with typical/baseline likelihood of Restless legs syndrome in migraine without aura — no copies of the reported risk allele. (GWAS Catalog, Ann Clin Transl Neurol 2020, PMID:32918390)
Source: GWAS Catalog, Ann Clin Transl Neurol 2020, PMID:32918390
Questions about rs76770509
What is rs76770509?
rs76770509 is a single position in the genome, in or near the near PMCH gene. Published research associates it with restless legs syndrome in migraine without aura. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs76770509 linked to?
On MyGeneLog this position is linked to Restless Legs Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does having rs76770509 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs76770509 come from?
GWAS Catalog, Ann Clin Transl Neurol 2020, PMID:32918390. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.