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alpha-Fetoprotein levels

near RASSF6 · rs76731854

What the study found

Who was studied 7,747 Korean ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.528 ng/mL lower; p = 4 × 10−13.

How common The T allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 4, band 4q13.3 — between genes, 33.7 kb from RASSF6.

What each result means

C/C No copy of the version the research linked to alpha-Fetoprotein levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to alpha-Fetoprotein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to alpha-Fetoprotein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs76731854

What is rs76731854?

rs76731854 is a single position in the genome, in or near the near RASSF6 gene. Published research associates it with alpha-fetoprotein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs76731854 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76731854 come from?

GWAS Catalog, Scientific reports 2022, PMID:35121771. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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alpha-Fetoprotein levels (rs76731854). MyGeneLog™. https://www.mygenelog.com/variants/rs76731854

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