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White blood cell count

TBC1D14 · rs7668673

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0135 lower (95% confidence interval 0.011-0.016); p = 2 × 10⁻¹⁸.

Where it sits Chromosome 4, band 4p16.1 — in an intron of TBC1D14.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of White blood cell count — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with White blood cell count.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of White blood cell count compared to the general population.

Source

Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures

Jee YH, Wang Y, Jung KJ, Lee JY, Kimm H, Duan R, Price AL, Martin AR, Kraft P

Nature communications · 2025 · PMID 40436827 · open access

Questions about rs7668673

What is rs7668673?

rs7668673 is a single position in the genome, in or near the TBC1D14 gene. Published research associates it with white blood cell count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7668673 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7668673 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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White blood cell count (rs7668673). MyGeneLog™. https://www.mygenelog.com/variants/rs7668673

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