THADA · rs76684055
Where this position leads
Condition: Inguinal Hernia
What the study found
Who was studied 18,791 European ancestry cases, 93,955 European ancestry controls.
The effect Each copy of the G allele carried 1.12 times the odds of Inguinal hernia (95% confidence interval 1.08-1.16); p = 3 × 10−10.
How common The G allele had a frequency of about 90% in the people studied.
Where it sits Chromosome 2, band 2p21 — in an intron of THADA.
rs76684055 is a single position in the genome, in or near the THADA gene. Published research associates it with inguinal hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Inguinal Hernia. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PloS one 2022, PMID:36584111. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Inguinal hernia (rs76684055). MyGeneLog™. https://www.mygenelog.com/variants/rs76684055