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Who was studied 22,474 European ancestry cases, 774,187 European ancestry controls.
The effect
Each copy of the T allele carried 0.89 times the odds of Atopic dermatitis (95% confidence interval 0.86-0.92); p = 6 × 10−11.
How common The T allele had a frequency of about 9% in the people studied.
Where it sits Chromosome 4, band 4q27 — between genes, 23.7 kb from RN7SL335P.
What each result means
C/CNo copy of the version the research linked to Atopic dermatitis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Atopic dermatitis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Atopic dermatitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of allergy and clinical immunology · 2022 · PMID 34454985
Questions about rs7666843
What is rs7666843?
rs7666843 is a single position in the genome, in or near the near RN7SL335P gene. Published research associates it with atopic dermatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7666843 linked to?
On MyGeneLog this position is linked to Atopic Dermatitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs7666843 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7666843 come from?
GWAS Catalog, The Journal of allergy and clinical immunology 2022, PMID:34454985. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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