0 413Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others3Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 24,087 European ancestry cases, 55,058 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 5.6 z-score higher; p = 2 × 10−8.
Where it sits Chromosome 4, band 4p15.33 — between genes, 18.9 kb from LINC02360.
What each result means
A/ATwo copies of the version the research linked to Alzheimer's disease (late onset). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Alzheimer's disease (late onset). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Alzheimer's disease (late onset). This is the starting point the study compared everyone against.
rs7657553 is a single position in the genome, in or near the HS3ST1 gene. Published research associates it with alzheimer's disease (late onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7657553 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs7657553 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7657553 come from?
GWAS Catalog, Nature genetics 2019, PMID:30617256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 413Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others3Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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