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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 29,580 European ancestry individuals, 14,462 Asian ancestry individuals; replicated in 88,218 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.014 mm higher; p = 2 × 10−38.
How common The A allele had a frequency of about 39% in the people studied.
Where it sits Chromosome 4, band 4q13.3 — between genes, 38.2 kb from ADAMTS3.
What each result means
A/ATwo copies of the version the research linked to Corneal curvature. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Corneal curvature. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Corneal curvature. This is the starting point the study compared everyone against.
Communications biology · 2020 · PMID 32193507 · open access
Questions about rs7657200
What is rs7657200?
rs7657200 is a single position in the genome, in or near the near ADAMTS3 gene. Published research associates it with corneal curvature. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7657200 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7657200 come from?
GWAS Catalog, Communications biology 2020, PMID:32193507. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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