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Gut microbiota (bacterial taxa)

SLC2A9 · rs7656342

Where this position leads

Condition: Gut Microbiota

rs7656342 Condition: Gut Microbiota Gut Microbiota Condition rs7656342 rs7656342 SLC2A9

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−9, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 1,812 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.39 higher (95% confidence interval -); p = 3 × 10−9.

Where it sits Chromosome 4, band 4p16.1 — inside SLC2A9.

What each result means

A/A Two copies of the version the research linked to Gut microbiota (bacterial taxa). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Gut microbiota (bacterial taxa). That is a smaller link than two copies.
G/G No copy of the version the research linked to Gut microbiota (bacterial taxa). This is the starting point the study compared everyone against.
Source

Questions about rs7656342

What is rs7656342?

rs7656342 is a single position in the genome, in or near the SLC2A9 gene. Published research associates it with gut microbiota (bacterial taxa). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7656342 linked to?

On MyGeneLog this position is linked to Gut Microbiota. The research behind each link, and its sources, are set out on that condition page.

Does having rs7656342 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7656342 come from?

GWAS Catalog, Nat Genet 2016, PMID:27723756. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Gut microbiota (bacterial taxa) (rs7656342). MyGeneLog™. https://www.mygenelog.com/variants/rs7656342

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