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Medication use (thyroid preparations)

RP11-503L19.1 · rs7655751

What the study found

Who was studied 24,832 European ancestry cases, 280,750 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.132 lower (95% confidence interval 0.11-0.15); p = 2 × 10−32.

How common The T allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 4, band 4q31.23 — between genes, 8.4 kb from ATP5MGP4.

What each result means

C/C No copy of the version the research linked to Medication use (thyroid preparations). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Medication use (thyroid preparations). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Medication use (thyroid preparations). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7655751

What is rs7655751?

rs7655751 is a single position in the genome, in or near the RP11-503L19.1 gene. Published research associates it with medication use (thyroid preparations). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7655751 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7655751 come from?

GWAS Catalog, Nature communications 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Medication use (thyroid preparations) (rs7655751). MyGeneLog™. https://www.mygenelog.com/variants/rs7655751

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