Gene Knowledge Graph
UTC
Standard

Urinary albumin excretion

SHROOM3 · rs7654754

Where this position leads

Condition: Kidney Function

rs7654754 Condition: Kidney Function Kidney Function Condition rs7654754 rs7654754 SHROOM3

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Urinary albumin excretion — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Urinary albumin excretion.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Urinary albumin excretion compared to the general population.
Source
Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure
Haas ME, Aragam KG, Emdin CA, Bick AG, Hemani G, Davey Smith G, Kathiresan S
International Consortium for Blood Pressure
American journal of human genetics · 2018 · PMID 30220432

Questions about rs7654754

What is rs7654754?

rs7654754 is a single position in the genome, in or near the SHROOM3 gene. Published research associates it with urinary albumin excretion. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7654754 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs7654754 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7654754 come from?

GWAS Catalog, Am J Hum Genet 2018, PMID:30220432. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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