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Who was studied 153,950 Korean ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.078 higher (95% confidence interval 0.06-0.096); p = 8 × 10−18.
How common The A allele had a frequency of about 11% in the people studied.
Where it sits Chromosome 12, band 12p12.2 — between genes, 82.1 kb from PDE3A-AS1.
What each result means
A/ATwo copies of the version the research linked to Adiponectin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Adiponectin levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Adiponectin levels. This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40436827 · open access
Questions about rs76545872
What is rs76545872?
rs76545872 is a single position in the genome, in or near the near PDE3A-AS1 gene. Published research associates it with adiponectin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs76545872 linked to?
On MyGeneLog this position is linked to Adiponectin Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs76545872 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs76545872 come from?
GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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