Sensitive

Thrombosis

FGG · rs7654093

Where this position leads

Condition: Ischaemic Stroke

rs7654093 Condition: Ischaemic Stroke Ischaemic Stroke Condition rs7654093 rs7654093 FGG

What the study found

Who was studied 6,135 European ancestry cases, 252,827 European ancestry controls.

The effect Each copy of the T allele carried 1.22 times the odds of Thrombosis (95% confidence interval 1.166- 1.267); p = 2 × 10−19.

How common The T allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 4, band 4q32.1 — between genes, 2.5 kb from LOC124900169.

What each result means

A/A No copy of the version the research linked to Thrombosis. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Thrombosis. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Thrombosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7654093

What is rs7654093?

rs7654093 is a single position in the genome, in or near the FGG gene. Published research associates it with thrombosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7654093 linked to?

On MyGeneLog this position is linked to Ischaemic Stroke. The research behind each link, and its sources, are set out on that condition page.

Does having rs7654093 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7654093 come from?

GWAS Catalog, Hum Mol Genet 2016, PMID:26908601. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Thrombosis (rs7654093). MyGeneLog™. https://www.mygenelog.com/variants/rs7654093

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