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X-21470 levels

near TPRX2 · rs76531193

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 6,136 Finnish ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.43 lower; p = 2 × 10−64.

Where it sits Chromosome 19, band 19q13.33 — between genes, 1.8 kb from TPRX2.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of X-21470 levels compared to the general population.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with X-21470 levels.
T/T Published research associates this genotype with typical/baseline likelihood of X-21470 levels — no copies of the reported risk allele.
Source
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci
Yin X, Chan LS, Bose D, Jackson AU, VandeHaar P, Locke AE, Fuchsberger C, Stringham HM, Welch R, Yu K, Fernandes Silva L, Service SK
and 25 more — show all
Zhang D, Hector EC, Young E, Ganel L, Das I, Abel H, Erdos MR, Bonnycastle LL, Kuusisto J, Stitziel NO, Hall IM, Wagner GR, Kang J, Morrison J, Burant CF, Collins FS, Ripatti S, Palotie A, Freimer NB, Mohlke KL, Scott LJ, Wen X, Fauman EB, Laakso M, Boehnke M
FinnGen
Nature communications · 2022 · PMID 35347128 · open access

Questions about rs76531193

What is rs76531193?

rs76531193 is a single position in the genome, in or near the near TPRX2 gene. Published research associates it with x-21470 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs76531193 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76531193 come from?

GWAS Catalog, Nature communications 2022, PMID:35347128. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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X-21470 levels (rs76531193). MyGeneLog™. https://www.mygenelog.com/variants/rs76531193

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