Standard
IgG glycosylation
ST6GAL1 · rs7652995
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of IgG glycosylation — no copies of the reported risk allele. (GWAS Catalog, PLoS Genet 2013, PMID:23382691)
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with IgG glycosylation. (GWAS Catalog, PLoS Genet 2013, PMID:23382691)
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of IgG glycosylation compared to the general population. (GWAS Catalog, PLoS Genet 2013, PMID:23382691)
Source
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers
Lauc G,
Huffman JE,
Pučić M,
Zgaga L,
Adamczyk B,
Mužinić A,
Novokmet M,
Polašek O,
Gornik O,
Krištić J,
Keser T,
Vitart V
and 27 more — show all
Scheijen B,
Uh HW,
Molokhia M,
Patrick AL,
McKeigue P,
Kolčić I,
Lukić IK,
Swann O,
van Leeuwen FN,
Ruhaak LR,
Houwing-Duistermaat JJ,
Slagboom PE,
Beekman M,
de Craen AJ,
Deelder AM,
Zeng Q,
Wang W,
Hastie ND,
Gyllensten U,
Wilson JF,
Wuhrer M,
Wright AF,
Rudd PM,
Hayward C,
Aulchenko Y,
Campbell H,
Rudan I
PLoS genetics · 2013 · PMID 23382691 · open access
Questions about rs7652995
What is rs7652995?
rs7652995 is a single position in the genome, in or near the ST6GAL1 gene. Published research associates it with igg glycosylation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7652995 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7652995 come from?
GWAS Catalog, PLoS Genet 2013, PMID:23382691. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants