Standard

Medication use (beta blocking agents)

RYBP · rs7652333

Where this position leads

Condition: Medication Use as a Genetic Trait

rs7652333 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs7652333 rs7652333 RYBP

What the study found

Who was studied 31,700 European ancestry cases, 192,324 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0474 higher (95% confidence interval 0.031-0.064); p = 2 × 10−8.

How common The T allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 3, band 3p13 — between genes, 3.6 kb from RYBP.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Medication use (beta blocking agents) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (beta blocking agents).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (beta blocking agents) compared to the general population.
Source

Questions about rs7652333

What is rs7652333?

rs7652333 is a single position in the genome, in or near the RYBP gene. Published research associates it with medication use (beta blocking agents). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7652333 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs7652333 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7652333 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Medication use (beta blocking agents) (rs7652333). MyGeneLog™. https://www.mygenelog.com/variants/rs7652333

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