Standard

High density lipoprotein cholesterol levels

MYO5B · rs76511906

What the study found

Who was studied 1,320,016 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0937 higher (95% confidence interval 0.081-0.107); p = 2 × 10−27.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 18, band 18q21.1 — in an intron of MYO5B.

What each result means

A/A Two copies of the version the research linked to High density lipoprotein cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to High density lipoprotein cholesterol levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to High density lipoprotein cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs76511906

What is rs76511906?

rs76511906 is a single position in the genome, in or near the MYO5B gene. Published research associates it with high density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs76511906 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76511906 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

High density lipoprotein cholesterol levels (rs76511906). MyGeneLog™. https://www.mygenelog.com/variants/rs76511906

← See all variants