Standard

Creatinine levels

near TMEM41A-DT · rs7649167

Where this position leads

Condition: Kidney Function

rs7649167 Condition: Kidney Function Kidney Function Condition rs7649167 rs7649167 near TMEM41A…

What the study found

Who was studied 110,051 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0237 lower (95% confidence interval 0.016-0.031); p = 5 × 10−10.

How common The T allele had a frequency of about 68% in the people studied.

Where it sits Chromosome 3, band 3q27.2 — between genes, 4.3 kb from TMEM41A-DT.

What each result means

C/C No copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7649167

What is rs7649167?

rs7649167 is a single position in the genome, in or near the near TMEM41A-DT gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7649167 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs7649167 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7649167 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Creatinine levels (rs7649167). MyGeneLog™. https://www.mygenelog.com/variants/rs7649167

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