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C-reactive protein levels

near COX6A1 · rs76475417

Where this position leads

Condition: C-Reactive Protein Levels

rs76475417 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs76475417 rs76475417 near COX6A1

What the study found

Who was studied 341,805 European ancestry individuals, 6,006 African ancestry individuals, 7,316 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.05 lower (95% confidence interval 0.036-0.064); p = 2 × 10−12.

Where it sits Chromosome 12, band 12q24.31 — between genes, 5.1 kb from COX6A1.

What each result means

A/A Two copies of the version the research linked to C-reactive protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to C-reactive protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to C-reactive protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs76475417

What is rs76475417?

rs76475417 is a single position in the genome, in or near the near COX6A1 gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs76475417 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs76475417 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76475417 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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C-reactive protein levels (rs76475417). MyGeneLog™. https://www.mygenelog.com/variants/rs76475417

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