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Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256)

BSN · rs7646288

Where this position leads

Condition: Celiac Disease

rs7646288 Condition: Celiac Disease Celiac Disease Condition rs7646288 rs7646288 BSN

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.018 lower (95% confidence interval 0.013-0.023); p = 6 × 10−12.

How common The A allele had a frequency of about 81% in the people studied.

Where it sits Chromosome 3, band 3p21.31 — in an intron of BSN.

What each result means

A/A Two copies of the version the research linked to Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256). That is a smaller link than two copies.
G/G No copy of the version the research linked to Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256). This is the starting point the study compared everyone against.
Source

Questions about rs7646288

What is rs7646288?

rs7646288 is a single position in the genome, in or near the BSN gene. Published research associates it with forced expiratory volume in 1 second fev1 z score (ukb data field 20256). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7646288 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs7646288 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7646288 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256) (rs7646288). MyGeneLog™. https://www.mygenelog.com/variants/rs7646288

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