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Omega-3 fatty acid levels

SLC2A2 · rs7643425

Where this position leads

Drug: Metformin

rs7643425 Drug: Metformin Metformin Drug rs7643425 rs7643425 SLC2A2

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 2 × 10−10.

Where it sits Chromosome 3, band 3q26.2 — in an intron of SLC2A2.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Omega-3 fatty acid levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Omega-3 fatty acid levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Omega-3 fatty acid levels compared to the general population.
Source

Questions about rs7643425

What is rs7643425?

rs7643425 is a single position in the genome, in or near the SLC2A2 gene. Published research associates it with omega-3 fatty acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does rs7643425 affect how medicines work?

SLC2A2 carries pharmacogenomic findings for Metformin. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs7643425 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7643425 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Omega-3 fatty acid levels (rs7643425). MyGeneLog™. https://www.mygenelog.com/variants/rs7643425

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