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Post-surgical neuropathic pain

KCNN2 · rs76420936

What the study found

Who was studied 695 European ancestry cases, 12,905 European ancestry controls.

The effect Each copy of the G allele carried 0.19 times the odds of Post-surgical neuropathic pain (95% confidence interval 0.11-0.34); p = 3 × 10−8.

Where it sits Chromosome 5, band 5q22.3 — in an intron of KCNN2.

What each result means

A/A No copy of the version the research linked to Post-surgical neuropathic pain. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Post-surgical neuropathic pain. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Post-surgical neuropathic pain. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs76420936

What is rs76420936?

rs76420936 is a single position in the genome, in or near the KCNN2 gene. Published research associates it with post-surgical neuropathic pain. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs76420936 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76420936 come from?

GWAS Catalog, Pain 2026, PMID:40899795. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Post-surgical neuropathic pain (rs76420936). MyGeneLog™. https://www.mygenelog.com/variants/rs76420936

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