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Who was studied 768 Hispanic or Latin American cases, 58,733 Hispanic or Latin American controls, 31,142 European ancestry cases, 404,406 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.189 higher (95% confidence interval 0.15-0.22); p = 1 × 10−35.
How common The A allele had a frequency of about 89% in the people studied.
Where it sits Chromosome 10, band 10p14 — in an intron of LINC02676.
What each result means
A/ATwo copies of the version the research linked to Basal cell carcinoma (PheCode 172.21). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Basal cell carcinoma (PheCode 172.21). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Basal cell carcinoma (PheCode 172.21). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs76407406
What is rs76407406?
rs76407406 is a single position in the genome, in or near the LINC02676 gene. Published research associates it with basal cell carcinoma (phecode 172.21). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs76407406 linked to?
On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs76407406 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs76407406 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1412110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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