G/GPublished research associates this genotype with typical/baseline likelihood of High density lipoprotein cholesterol levels — no copies of the reported risk allele.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with High density lipoprotein cholesterol levels.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of High density lipoprotein cholesterol levels compared to the general population.
Nature genetics · 2018 · PMID 29507422 · open access
Questions about rs76376137
What is rs76376137?
rs76376137 is a single position in the genome, in or near the near HMGA1 gene. Published research associates it with high density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs76376137 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs76376137 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs76376137 come from?
GWAS Catalog, Nat Genet 2018, PMID:29507422. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.