Standard

Blood glucose levels

SPC25 · rs76372731

Where this position leads

Condition: Gout

rs76372731 Condition: Gout Gout Condition rs76372731 rs76372731 SPC25

What the study found

Who was studied 313,125 European ancestry individuals, 5,568 African ancestry individuals, 6,693 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.112 lower (95% confidence interval 0.095-0.129); p = 1 × 10−36.

Where it sits Chromosome 2, band 2q24.3 — in a regulatory region of SPC25.

What each result means

C/C Two copies of the version the research linked to Blood glucose levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Blood glucose levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Blood glucose levels. This is the starting point the study compared everyone against.
Source

Questions about rs76372731

What is rs76372731?

rs76372731 is a single position in the genome, in or near the SPC25 gene. Published research associates it with blood glucose levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs76372731 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs76372731 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76372731 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Blood glucose levels (rs76372731). MyGeneLog™. https://www.mygenelog.com/variants/rs76372731

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