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Who was studied 35,156 European ancestry cases, 846,868 European ancestry controls, 2,385 Japanese ancestry cases, 209,651 Japanese ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.495 higher (95% confidence interval 0.35-0.65); p = 9 × 10−11.
Where it sits Chromosome 12, band 12q13.2 — between genes, 9.7 kb from RPS26.
What each result means
A/ATwo copies of the version the research linked to Atopic dermatitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Atopic dermatitis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Atopic dermatitis. This is the starting point the study compared everyone against.
The Journal of investigative dermatology · 2024 · PMID 38663478
Questions about rs763581386
What is rs763581386?
rs763581386 is a single position in the genome, in or near the near RPS26 gene. Published research associates it with atopic dermatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs763581386 linked to?
On MyGeneLog this position is linked to Atopic Dermatitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs763581386 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs763581386 come from?
GWAS Catalog, The Journal of investigative dermatology 2024, PMID:38663478. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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